第七节 颅内压监测
脑灌注压
麻醉
创伤性脑损伤
重症监护医学
血压
脑自动调节
脑脊液
作者
Thomas Heldt,Tommaso Zoerle,Daniel Teichmann,Nino Stocchetti
标识
DOI:10.1146/annurev-bioeng-060418-052257
摘要
Patients with acute brain injuries tend to be physiologically unstable and at risk of rapid and potentially life-threatening decompensation due to shifts in intracranial compartment volumes and consequent intracranial hypertension. Invasive intracranial pressure (ICP) monitoring therefore remains a cornerstone of modern neurocritical care, despite the attendant risks of infection and damage to brain tissue arising from the surgical placement of a catheter or pressure transducer into the cerebrospinal fluid or brain tissue compartments. In addition to ICP monitoring, tracking of the intracranial capacity to buffer shifts in compartment volumes would help in the assessment of patient state, inform clinical decision making, and guide therapeutic interventions. We review the anatomy, physiology, and current technology relevant to clinical management of patients with acute brain injury and outline unmet clinical needs to advance patient monitoring in neurocritical care.
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