Synthesis of Double-armed Azaoligocycles Based upon High Pressure Aromatic Nucleophilic Substitution Reactions

A variety of double-armed azaoligocycles were prepared through high pressure S Ar reactions (0.8 GPa, 1 0 0 ~~) of homo-N piperazlne wrth five-and SIX-membered heteroaromatic halides, the yields being good to excellent when the halides are activated by electronic effects.