硝化作用
取代基
电泳剂
硝基
卤化
化学
戒指(化学)
药物化学
有机化学
催化作用
烷基
作者
Michael Davis,Alex William White
出处
期刊:Journal of the Chemical Society. C.Organic
[The Royal Society of Chemistry]
日期:1969-01-01
卷期号: (16): 2189-2189
被引量:7
摘要
Bromination of 2,1-benzisothiazole (I) under conditions in which Br+ is the electrophilic species gives a mixture of 5- and 7-bromo-2,1-benzisothiazole, together with a smaller quantity of 4,7-dibromo-2,1-benzisothiazole. Nitration of 2,1-benzisothiazole affords mainly 5-nitro-2,1-benzisothiazole with smaller quantities of the 7-nitro- and 4-nitro-isomers. Nitration of monosubstituted 2,1-benzisothiazoles gives products which indicate that the substituent group already present in the benzenoid ring is the decisive directing influence.
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