兴奋-收缩耦合
心肌细胞
钙
心肌细胞
细胞器
激发
联轴节(管道)
心肌
收缩(语法)
生物物理学
物理
化学
内科学
解剖
生物
细胞生物学
材料科学
医学
生物化学
量子力学
冶金
出处
期刊:Nature
[Springer Nature]
日期:2002-01-01
卷期号:415 (6868): 198-205
被引量:3986
摘要
Of the ions involved in the intricate workings of the heart, calcium is considered perhaps the most important. It is crucial to the very process that enables the chambers of the heart to contract and relax, a process called excitation-contraction coupling. It is important to understand in quantitative detail exactly how calcium is moved around the various organelles of the myocyte in order to bring about excitation-contraction coupling if we are to understand the basic physiology of heart function. Furthermore, spatial microdomains within the cell are important in localizing the molecular players that orchestrate cardiac function.
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