痴笑发作
海马硬化
符号学
脑电图
癫痫
颞叶
癫痫外科
医学
心理学
麻醉
神经科学
下丘脑错构瘤
性早熟
内科学
激素
作者
Stjepana Kovač,Beate Diehl,Tim Wehner,Chiara Fois,N. Toms,Matthew C. Walker,John S. Duncan
出处
期刊:Epilepsia
[Wiley]
日期:2014-12-17
卷期号:56 (1)
被引量:39
摘要
Summary This study aimed to determine clinical features of adult patients with gelastic seizures recorded on video –electroencephalography (EEG) over a 5‐year period. We screened video‐ EEG telemetry reports for the occurrence of the term “gelastic” seizures, and assessed the semiology, EEG features, and duration of those seizures. Gelastic seizures were identified in 19 (0.8%) of 2,446 admissions. The presumed epileptogenic zone was in the hypothalamus in one third of the cases, temporal lobe epilepsy was diagnosed in another third, and the remainder of the cases presenting with gelastic seizures were classified as frontal, parietal lobe epilepsy or remained undetermined or were multifocal. Gelastic seizures were embedded in a semiology, with part of the seizure showing features of automotor seizures. A small proportion of patients underwent epilepsy surgery. Outcome of epilepsy surgery was related to the underlying pathology; two patients with hippocampal sclerosis had good outcomes following temporal lobe resection and one of four patients with hypothalamic hamartomas undergoing gamma knife surgery had a good outcome.
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