Lymphadenopathy Associated With Severe Hypertriglyceridemia

To the Editor.—

In discussion of diagnostic entities that are defined in large part by histopathologic interpretation, there ought to be a careful and complete discussion of histopathologic findings. Further, contentions based on these findings should be carefully discussed and supported with references from appropriate literature. Nowhere is this more true than in diseases involving lymph nodes. Therefore, I am not convinced that Leaf et al¹succeeded in their description of the first case of "Lymphadenopathy Associated With Severe Hypertriglyceridemia." No light photomicrographs are included to demonstrate the characteristic findings in this "new" lymphadenopathy. No direct pathologist input is given, so we are left with the authors' interpretation of pathology reports. If I am reading their interpretation fairly, then the bilateral axillary lymph node biopsies in this middle-aged woman demonstrated fatty replacement of the nodes (grossly noted to float in formaldehyde solution) and lipophagic reaction. These two findings are