急性呼吸窘迫综合征
医学
急性呼吸窘迫
重症监护医学
肺
弥漫性肺泡损伤
趋化因子受体
发病机制
机制(生物学)
趋化因子
免疫学
炎症
内科学
认识论
哲学
作者
Yao Shen,Diane Wang,Xiangdong Wang
摘要
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe inflammatory lung diseases associated with very high mortality, and are the most common and earliest organ dysfunctions in the development of multiple organ dysfunction syndrome. The NIH estimates that more than 4.5 million people suffer from ALI/ARDS per year. Although the American–European Consensus Conference definition has been widely used for approximately 40 years, it still has some limitations that may impact on the conduct of clinical research and management of patients with ALI/ARDS. This article will focus on the role of CC chemokine receptor 2 and IL-8 in the pathogenesis and resolution in ALI/ARDS.
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