The differences indicate that A/Vietnam/14011801/2014 is a novel reassortant virus between clades 2. 3.2.1a and 2.3.2.1c, between clades 1.1.2 and 2.3.2.1c, or both (Figure). This novel reassortant virus has not been reported in poultry in Vietnam, although novel reassortants between clade 1.1. EPI624927-EPI624934; and A/ Vietnam/14012902/2014) (6). These novel reassortment viruses were first identified in human, animal, and environmental samples in Cambodia in 2013 (5). Other novel gene reassortments in clade 2.3.2.1 viruses have been previously reported (10), and new clade 2.3.4.4 viruses have been observed in Vietnam since 2014.