Possibility of Müller Cell Dysfunction as the Pathogenesis of Paclitaxel Maculopathy.

Cystoid macular edema (CME) without leakage is an adverse complication of paclitaxel administration in patients with cancer. However, the mechanism of non-leaking CME has been unclear. The authors report the case of a 66-year-old man who developed non-leaking CME during treatment with paclitaxel for gastric cancer. This case report suggests possible pathogenesis of paclitaxel-induced CME without evidence of leakage at angiography from the data of electroretinogram.