硬脑膜
医学
脊髓
中枢神经系统
脑植入物
神经科学
植入
生物医学工程
解剖
外科
心理学
精神科
内分泌学
作者
Jocelyne Bloch,Stéphanie Lacour,Grégoire Courtine
出处
期刊:JAMA Neurology
[American Medical Association]
日期:2017-04-01
卷期号:74 (4): 470-470
被引量:13
标识
DOI:10.1001/jamaneurol.2016.5767
摘要
A growing number of neurologic treatments rely on neural implants capable of delivering electrical and chemical stimulation to targeted regions of the central nervous system for extended periods.To assess the potential of a novel class of multimodal neural implants, termed electronic dura mater or e-dura, to fulfill this need.Results from preclinical applications of e-dura implants and clinical evidence.The silicone-based implant e-dura embeds interconnects, electrodes, and chemotrodes that are entirely stretchable. These unique mechanical properties allow e-dura to conform to the circumvolutions of the brain and spinal cord without damaging neural tissues or triggering foreign body reactions.Although challenges lie ahead to reach clinical fruition, the unique mechanical properties and integrated modalities of e-dura provide future opportunities to treat or alleviate neurologic deficits.
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