Research progress on induced differentiation of embryonic stem cells

Embryonic stem cells were derived from the inner cell masses of cultured blastocysts in mammal and capable of unlimited,undifferentiated proliferation in vitro .At the same time,embryonic stem cells could also be directly induced to differentiate in culture into a variety of cell types under appropriate conditions.Homogeneous populations of cells produced by directed differentiation in vitro could be applied to study the cell replacement therapies of disease,etc.This paper elaborated signaling mechanisms regulating self renewal and differentiation on induced differentiation of embryonic stem cells,methods of induced differentiation of embryonic stem cells,research progress and prospects on induced differentiation of embryonic stem cells.