In lot of water treatment plants, biological contact oxidation process has been or is to be adopted for water pretreatment, so as to improve water quality. Due to lack of full knowledge of biochemical treatment and the limitation in traditional prechlorination conception, the operated biochemical process fails to efficiently remove the organic pollutants. Analysis was made for the experimental data measured under the conditions whether chlorination was adopted. Based on the analysis, the entire process biological oxidation (EPBO) has been proposed.