This paper adopts reactive disperse red KR-3B and reactive disperse KR-BR in NC supercritical CO2 dyeing apparatus to dye wool loose,analysis the influence of dyeing temperature,dye pressure,dyeing time on dyeing K/S value.After tests,the technological paramers are the reactive disperse red dyeing process parameters are: dyeing temperature 100 ℃,dyeing pressure 22 MPa,dyeing time 50 min,reactive disperse KR-BR dyeing process parameters are: dyeing temperature 100 ℃,dyeing pressure 24 MPa,dyeing time 70 min.The apparent morphology before and after dyeing,dyes are observed by a scanning electron microscope,after dyeing the dyes spherical structure split,the apparent change in the structure.The rubbing fastness and the washing fastness are in line with the national standards.