Abstract 17161: Inflammatory Serine Protease Inhibition Attenuates Myocyte Apoptosis and Cardiac Dysfunction via Intervention of Peroxisome Proliferator-activated Receptor Gamma-induced Lipotoxicity and Inflammation in High Fat Diet-induced Diabetic Cardiomyopathy

Background: Diet consisting of high percentage of fat induces lipotoxicity, leading to type II diabetes and diabetic cardiomyopathy (DCM). The mechanism by which high fat diet (HFD) mediated lipoto...