灭菌(经济)
嗜热脂肪地芽孢杆菌
孢子
过氧化氢
微生物学
化学
金黄色葡萄球菌
铜绿假单胞菌
环氧乙烷
食品科学
细菌
生物
有机化学
外汇
共聚物
货币经济学
外汇市场
聚合物
酶
经济
遗传学
嗜热菌
作者
William A. Rutala,Maria F. Gergen,Emily Sickbert-Bennett,David J. Weber
摘要
Abstract Objective: To compare the microbicidal activity of low-temperature sterilization technologies (vaporized hydrogen peroxide [VHP], ethylene oxide [ETO], and hydrogen peroxide gas plasma [HPGP]) to steam sterilization in the presence of salt and serum to simulate inadequate precleaning. Methods: Test carriers were inoculated with Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus , vancomycin-resistant Enterococcus, Mycobacterium terrae, Bacillus atrophaeus spores, Geobacillus stearothermophilus spores, or Clostridiodes difficile spores in the presence of salt and serum and then subjected to 4 sterilization technologies: steam, ETO, VHP and HPGP. Results: Steam, ETO, and HPGP sterilization techniques were capable of inactivating the test organisms on stainless steel carriers with a failure rate of 0% (0 of 220), 1.9% (6 of 310), and 1.9% (5 of 270), respectively. The failure rate for VHP was 76.3% (206 of 270). Conclusion: Steam sterilization is the most effective and had the largest margin of safety, followed by ETO and HPGP, but VHP showed much less efficacy.
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