医学
生活质量(医疗保健)
指甲病
梅德林
皮肤病科
重症监护医学
政治学
护理部
法学
银屑病
作者
Claire Stewart,Leah Algu,Rakhshan Kamran,Cameron F. Leveille,Khizar Abid,Charlene Rae,Shari R. Lipner
标识
DOI:10.1016/j.jaad.2020.05.143
摘要
Background
Onychomycosis is the most common nail disorder, often causing physical, emotional, and aesthetic consequences. The effect of both the condition itself and treatment on quality of life has not been well studied. Objective
The objectives of this study were to systematically review the available literature describing the effect of onychomycosis and treatment on quality of life. Methods
We performed a search of the onychomycosis literature published before April 13, 2020. Articles were included in the review if primary data were presented, patient-reported outcome measures were used, and onychomycosis was specifically examined. Results
Thirty studies were included in the final analysis. Poorest quality-of-life scores were associated with women and fingernail involvement. Quality-of-life scores improved from baseline with all treatment types; there were greater improvements reported with oral treatments compared with topical ones. Conclusions
This review affirms that onychomycosis significantly influences quality of life, warranting effective treatment. All treatments resulted in quality-of-life improvements; however, studies on oral and topical therapies were of higher quality than those evaluating devices. Increased efforts are needed to understand the effect of the disease and therapy as assessed by validated, nail-specific outcome measures that accurately assess patients' cosmetic, physical, and social difficulties.
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