内科学
心脏病学
心肌病
心源性猝死
线粒体DNA
心力衰竭
生物能学
作者
Sara Ranjbarvaziri,Kristina B. Kooiker,Mathew Ellenberger,Giovanni Fajardo,Mingming Zhao,Alison Schroer Vander Roest,Rahel A. Woldeyes,Tiffany T. Koyano,Robyn Fong,Ning Ma,Lei Tian,Gavin M. Traber,Frandics P. Chan,John Perrino,Sushma Reddy,Wah Chiu,Joseph C. Wu,Joseph Woo,Kathleen M. Ruppel,James A. Spudich,Michael Snyder,Kévin Contrepois,Daniel Bernstein
出处
期刊：Circulation
[Lippincott Williams & Wilkins]
日期：2021-11-23
卷期号：144 (21): 1714-1731
标识
DOI：10.1161/circulationaha.121.053575
摘要
Background: Hypertrophic cardiomyopathy (HCM) is a complex disease partly explained by the effects of individual gene variants on sarcomeric protein biomechanics. At the cellular level, HCM mutatio...
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