Progress in the Studies on Synthesis and Biological Properties of Dithiocarbamates

Due to the diverse biological activities of dithiocarbamates, their researches of synthesis and pharmacological activity have been attracting considerable interest in the areas of organic chemistry and medicinal chemistry.In the aspect of synthetic methods, this review is focused on the progress in the synthesis of dithiocarbamates under the following conditions: strong alkali, weak alkali, using water or ionic liquids as solvent and solvent-free conditions.In the aspect of biological activities, This review is focused on the progress in the following activities of dithiocarbamates: the treatment of chronic alcoholism, antioxidant, antiviral, antibacterial, cholinesterase inhibition, cancer prevention and antitumor activities.