奥拉帕尼
彭布罗利珠单抗
医学
子宫内膜癌
肿瘤科
内科学
临床终点
PARP抑制剂
临床研究阶段
免疫疗法
置信区间
癌症
完全响应
临床试验
免疫系统
免疫检查点
前瞻性队列研究
作者
Maria M. Rubinstein,Jennifer Y. Ge,Q. Zhou,Alexia Iasonos,B Weigelt,P. Selenica,Daniel M. Muldoon,Chaitanya Bandlamudi,Caitlin Kaczynski,Viktoriya Paroder,Kelsey Higgins,Pooja Shah,S. Weissblum,Aleya Lyn,Y. Liu,Sminu Bose,Seth M. Cohen,Angela K. Green,Rachel N. Grisham,Chrisann Kyi
标识
DOI:10.1158/1078-0432.ccr-25-4467
摘要
The combination of olaparib plus pembrolizumab has promising activity with durable responses in patients with persistent or recurrent CN-H/p53-abnormal endometrial cancer. Molecular biomarkers may be helpful for patient selection in future studies of this combination.
科研通智能强力驱动
Strongly Powered by AbleSci AI