牛磺酸
氧化应激
细胞生物学
MAPK/ERK通路
信号转导
化学
氧化磷酸化
生物
生物化学
氨基酸
作者
Mengmeng Xu,Long Che,Kaiguo Gao,Li Wang,Xuefen Yang,Xiaolu Wen,Mengyun Li,Zongyong Jiang
摘要
The high incidence of oxidative stress in sows during late gestation and lactation affects mammary gland health, milk yield, and milk quality. Recently, we found that supplementing maternal diets with 1% taurine improved antioxidant capability and enhanced growth performance in offspring; however, the mechanisms underlying these are unknown. This study aimed to investigate the cytoprotective effects and the mechanism of taurine in mitigating oxidative stress in porcine mammary epithelial cells (PMECs). PMECs were pretreated with 0-2.0 mM taurine for 12 h and then subjected to oxidative injury with 500 μM hydrogen peroxide (H
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