FGF10型
成纤维细胞生长因子受体1
癌症研究
成纤维细胞生长因子
医学
基因敲除
小干扰RNA
类风湿性关节炎
关节炎
肿瘤坏死因子α
免疫学
生物
受体
细胞培养
内科学
转染
遗传学
作者
Xiaohui Meng,Zechuan Chen,Teng Li,Zhixing Nie,Haihui Han,Sheng Zhong,Zhinan Yin,Songtao Sun,Jun Xie,Jun Shen,Xirui Xu,Chenxin Gao,Lei Ran,Bo Xu,Zheng Xiang,Jianye Wang,Pengfei Sun,Pengfei Xin,A Xinyu,Chengbo Zhang
摘要
Fibroblast-like synoviocytes (FLSs) contribute to inflammation and joint damage in rheumatoid arthritis (RA). However, the regulatory mechanisms of FLSs in relapse and remission of RA remain unknown. Identifying FLS heterogeneity and their underlying pathogenic roles may lead to discovering novel disease-modifying antirheumatic drugs.
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