The Effects of Glucose‐Containing Dialysate on Cardiovascular and Cerebrovascular Outcome Events in Hemodialysis Patients

For patients with end-stage renal failure, hemodialysis is a crucial renal replacement therapy, which is meaningful to alleviate patients' symptoms and prolong survival. The principle of hemodialysis is to exchange the substances in the blood and dialysis solution through a semipermeable membrane and to discharge the excess water, metabolic waste, and electrolytes into the dialysis solution, which can balance the water, electrolytes, and acid-base. However, patients on maintenance hemodialysis are at high risk of developing cardiovascular and cerebrovascular diseases. Therefore, the composition of dialysis fluid has been widely studied, and the use of sugar-containing dialysis fluid can reduce the incidence of hypoglycemia, hypotension, and cardiovascular and cerebrovascular complications in hemodialysis patients. This article reviews the effects of current glucose-containing dialysate on cardiovascular and cerebrovascular outcome events in hemodialysis patients.