纳米团簇
荧光
牛血清白蛋白
纳米复合材料
铜
水溶液中的金属离子
猝灭(荧光)
生物矿化
材料科学
纳米颗粒
化学工程
金属
核化学
化学
纳米技术
色谱法
工程类
冶金
物理
量子力学
作者
Chuan Fan,Xiaoxia Lv,Fengjuan Liu,Luping Feng,Min Liu,Yuanyuan Cai,Huan Liu,Jingyi Wang,Yanli Yang,Hua Wang
出处
期刊:ACS Sensors
[American Chemical Society]
日期:2018-02-06
卷期号:3 (2): 441-450
被引量:93
标识
DOI:10.1021/acssensors.7b00874
摘要
Silver nanoclusters (AgNCs) were first coated with bovine serum albumin (BSA) and then encapsulated into porous metal–organic frameworks of ZIF-8 by the protein-mediated biomineralization process. Unexpectedly, the fluorescence intensities of the yielded AgNCs-BSA@ZIF-8 nanocomposites were discovered to be continuously enhanced during each of the BSA coating and ZIF-8 encapsulation steps. Compared to common AgNCs, greatly improved photostability and storage stability of AgNCs could also be expected. More importantly, having benefited from the ZIF-8 shells, the prepared nanocomposites could possess the specific accumulation and sensitive response to Cu2+ ions, resulting in the rational quenching of their fluorescence intensities. Moreover, AgNCs-BSA@ZIF-8 nanocomposites were coated onto the hydrophobic arraying slides toward a microdots array-based fluorimetric method for the fast and sensitive evaluation of Cu2+ ions. It was discovered that the developed fluorimetric strategy could ensure the high-throughput analysis of Cu2+ ions in wide pH range, and especially some harsh and high-salt media. It can allow for the detection of Cu2+ ions in blood with the concentrations ranging from 4.0 × 10–4 to 160 μM, thus serving as a new copper detection candidate to be widely applied in clinical test, food safety, and environmental monitoring fields.
科研通智能强力驱动
Strongly Powered by AbleSci AI