A Procedure for the Large Scale Preparation of Nε-Alloc-lysine and Nε-Alloc-Nα-Fmoc-lysine

Abstract This report describes a convenient procedure for a 100 g scale preparation of Fmoc-Lys(Alloc) in 85% yield. This method can be easily adapted to a near one-pot procedure with slightly reduced yields, without requiring the isolation of the intermediate Lys(Alloc).