医学
口腔粘膜下纤维性变
随机对照试验
临床试验
口腔医学
循证医学
替代医学
梅德林
药品
药物试验
重症监护医学
内科学
病理
药理学
牙科
政治学
法学
标识
DOI:10.1016/j.joms.2008.12.056
摘要
Purpose To review the literature on drug treatment of oral submucous fibrosis. Materials and Methods An electronic search was performed for articles published from January 1960 to August 2008. Results Only 17 publications were searched, and 15 publications showed a high level of evidence (6 randomized controlled trials, 4 clinical trials/controlled clinical trials, and 5 other experimental studies), with a total of 1,224 patients. Conclusions Few studies with high levels of evidence were found. It is quite difficult to compare or even combine their outcomes in a scientifically meaningful manner. Because of insufficient research data, there is a need for high-quality randomized, controlled trials in this area of medicine. To review the literature on drug treatment of oral submucous fibrosis. An electronic search was performed for articles published from January 1960 to August 2008. Only 17 publications were searched, and 15 publications showed a high level of evidence (6 randomized controlled trials, 4 clinical trials/controlled clinical trials, and 5 other experimental studies), with a total of 1,224 patients. Few studies with high levels of evidence were found. It is quite difficult to compare or even combine their outcomes in a scientifically meaningful manner. Because of insufficient research data, there is a need for high-quality randomized, controlled trials in this area of medicine.
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