一氧化氮
神经科学
长时程增强
中枢神经系统
疾病
氧化应激
调节器
精氨酸
病态的
医学
生物
内科学
生物化学
受体
基因
氨基酸
作者
Mayur Virarkar,Lini Alappat,Peter G. Bradford,Atif B. Awad
标识
DOI:10.1080/10408398.2011.573885
摘要
One of the main functions of L-arginine (ARG) is the synthesis of nitric oxide (NO). NO is an important regulator of physiological processes in the central nervous system (CNS). NO promotes optimal cerebral blood flow, consolidates memory processes, facilitates long-term potentiation, maintains sleep-wake cycles, and assists in normal olfaction. However, at pathological levels, NO adversely affects brain function producing nitroxidative stress and promoting development of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and other disorders of the CNS. This review summarizes current knowledge of the role of NO in the CNS and the role of diet in regulating the levels of NO.
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