Relationship BetweenRANKandRANKLGene Polymorphisms with Osteoporosis in Rheumatoid Arthritis Patients

Postmenopausal women with RA, carrying either the RANKL-290T allele or possessing the RANK 575CC genotype were more likely to develop osteoporosis. Moreover, our results suggested that the polymorphism 290C>T could be considered a risk factor for genetic susceptibility to osteoporosis and low BMD.