生物
计算生物学
基因
功能(生物学)
植物代谢
次生代谢
代谢工程
天然产物
进化生物学
遗传学
生物化学
生物合成
核糖核酸
作者
Chuansong Zhan,Shuangqian Shen,Chenkun Yang,Zhenhua Liu,Alisdair R. Fernie,Ian A. Graham,Jie Luo
标识
DOI:10.1016/j.tplants.2022.03.002
摘要
Secondary metabolism in plants gives rise to a vast array of small-molecule natural products. The discovery of operon-like gene clusters in plants has provided a new perspective on the evolution of specialized metabolism and the opportunity to rapidly advance the metabolic engineering of natural product production. Here, we review historical aspects of the study of plant metabolic gene clusters as well as general strategies for identifying plant metabolic gene clusters in the multi-omics era. We also emphasize the exploration of their natural variation and evolution, as well as new strategies for the prospecting of plant metabolic gene clusters and a deeper understanding of how their structure influences their function.
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