安普克
衰老
氧化应激
化学
锡尔图因
炎症
激酶
细胞生物学
蛋白激酶A
分子生物学
生物化学
生物
乙酰化
免疫学
基因
作者
Shuai Lü,Jinyi Zhou,Chen Yang,Xiaoxue Zhang,Yingying Shi,Jie Liu,Xintong Yan,Juanjuan Liang,Xianli Liu,Lan Luo,Da Zhou,Zhimin Yin
出处
期刊:Food & Function
[The Royal Society of Chemistry]
日期:2022-01-01
卷期号:13 (14): 7560-7571
被引量:23
摘要
γ-glutamylcysteine activates SIRT1 by activating AMPK, promoting the nuclear translocation of GAPDH, while inhibiting that of DBC1. SIRT1 activation causes the deacetylation of p53 in the nucleus and inhibits the protein levels of p21 and p16.
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