木虱
排泄
内科学
内分泌学
胆固醇
去壳
化学
粪便
碳水化合物
基础(医学)
食品科学
胰岛素
生物
医学
膳食纤维
植物
古生物学
作者
Zara D Abraham,Tara Mehta
出处
期刊:PubMed
日期:1988-01-01
卷期号:47 (1): 67-74
被引量:19
摘要
This study was conducted to determine the effect of psyllium husk on plasma total and lipoprotein cholesterol in healthy human subjects and to elucidate possible hypocholesterolemic mechanisms. Seven males were given a nutritionally controlled diet based on their usual intake for x = 3 wk followed by 3 wk in which 21 g/d per person psyllium husk was added to the basal diet. After 10 d and after 3 wk of psyllium supplementation, total, low-density, and high-density cholesterol were reduced (p less than 0.002, p less than 0.01, and p less than 0.03, respectively). Fecal steroid excretion, determined from 5-d collections, was not affected by psyllium supplementation. Although psyllium tended to delay lipid absorption, plasma triglycerides, retinyl esters, glucose, insulin, and glucagon quantitated during meal tolerance tests given on the last day of each diet period were not different (p greater than 0.05). Thus the cholesterol-lowering mechanism of psyllium may not involve increased bile acid excretion or decreases in nutrient absorption.
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