医学
接收机工作特性
眼外肌
曲线下面积
甲状腺
核医学
曲线下面积
内科学
T2弛豫
内分泌学
泌尿科
胃肠病学
眼科
磁共振成像
药代动力学
放射科
作者
Defu Li,Xuejun Guo,Jianguo Zeng,Huijie Feng,Tingting Zhu,Hongbing Li
出处
期刊:Current Medical Imaging Reviews
[Bentham Science]
日期:2024-04-18
卷期号:20
标识
DOI:10.2174/0115734056299907240404064636
摘要
Objective:: This study aimed to compare the parametric value of T2 with and without fat suppression (FS) on T2 mapping for the evaluation of extraocular muscles (EOMs) in mild thyroid-associated ophthalmopathy (TAO). Methods:: We prospectively recruited 44 consecutive patients with mild TAO seen between May 2020 and October 2022 and 26 healthy controls with no history of eye- or thyroid-related or other autoimmune diseases. Patients with mild TAO were subdivided into active and inactive groups based on their clinical activity scores. The T2 of each EOM was measured over a large and small area of interest on T2-mapping images with and without FS. Receiver operating characteristic (ROC) curves were used to evaluate the diagnostic efficacy of T2 for detecting TAO activity. Results:: The T2 was significantly and heterogeneously higher in the active group than in the inactive and control groups (P < 0.05). FS-T2-mapping images had better signal display within and at the edges of the EOMs than those without FS. It was possible to observe high-signal aggregation visible in the periphery of some EOMs, and the central part showed relatively low signals. The maximum T2 measured in small or large areas with and without FS had good diagnostic efficacy for TAO activity, with that of no-FS being better (the area under the ROC curve of the maximum T2 measured in a small area and a large area without FS was 1.0 and 1.0 and P values of < 0.001 and < 0.001, respectively). Conclusion:: Maximal T2 with or without FS can facilitate the early clinical detection of mild TAO activity. The maximum T2 in a small area can facilitate active staging of patients with mild TAO.
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