足细胞
狼疮性肾炎
系统性红斑狼疮
肾小球基底膜
补体系统
基底膜
医学
狭缝隔膜
免疫学
免疫系统
病态的
肾小球肾炎
振膜(声学)
肾炎
病理
肾
蛋白尿
内科学
物理
疾病
声学
扬声器
标识
DOI:10.1016/j.ymthe.2024.04.010
摘要
Lupus nephritis (LN) is a frequent and serious manifestation of systemic lupus erythematosus (SLE), affecting over 50% of clinical patients. Occurrence and progression of LN is the end result of complex interactions between regulation of immune responses and pathological processes involving renal resident cells. Podocytes, which comprise the glomerular filtration barrier (GFB), anchor to the basement membrane through foot process extensions and interact with adjacent podocytes to form the slit diaphragm.
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