医学
骨软化症
病理
成纤维细胞生长因子23
低磷血症
磁共振成像
神经肿瘤学
病变
脑膜瘤
间充质干细胞
放射科
内科学
骨质疏松症
钙
甲状旁腺激素
作者
James A D Shand,David Kim
出处
期刊:Case Reports
[BMJ]
日期:2022-11-01
卷期号:15 (11): e252412-e252412
标识
DOI:10.1136/bcr-2022-252412
摘要
A man in his 40s was referred with persistent hypophosphataemia and bony pain. A serum fibroblast growth factor 23 level was markedly elevated and a diagnosis of tumour-induced osteomalacia was considered. Whole body imaging revealed multiple insufficiency fractures but no osseus tumours. There was, however, a durally-based intracranial lesion whose imaging characteristics were consistent with a meningioma. The tumour was removed, leading to rapid normalisation of the patient's symptoms and serum markers. Histology confirmed a phosphaturic mesenchymal tumour. We review the literature regarding this rare clinical situation.
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