地方政府
脑电图
显著性(神经科学)
心理学
神经科学
听力学
医学
作者
Shuang Qiu,Xiaohan Lyu,Zheng Qin,Huiguang He,Richu Jin,Weiwei Peng
出处
期刊:Cerebral Cortex
[Oxford University Press]
日期:2023-04-27
卷期号:33 (13): 8594-8604
被引量:2
标识
DOI:10.1093/cercor/bhad143
摘要
Abstract Brain dynamics can be modeled by a sequence of transient, nonoverlapping patterns of quasi-stable electrical potentials named “microstates.” While electroencephalographic (EEG) microstates among patients with chronic pain remained inconsistent in the literature, this study characterizes the temporal dynamics of EEG microstates among healthy individuals during experimental sustained pain. We applied capsaicin (pain condition) or control (no-pain condition) cream to 58 healthy participants in different sessions and recorded resting-state EEG 15 min after application. We identified 4 canonical microstates (A–D) that are related to auditory, visual, salience, and attentional networks. Microstate C had less occurrence, as were bidirectional transitions between microstate C and microstates A and B during sustained pain. In contrast, sustained pain was associated with more frequent and longer duration of microsite D, as well as more bidirectional transitions between microstate D and microstates A and B. Microstate D duration positively correlated with intensity of ongoing pain. Sustained pain improved global integration within microstate C functional network, but weakened global integration and efficiency within microstate D functional network. These results suggest that sustained pain leads to an imbalance between processes that load on saliency (microstate C) and processes related to switching and reorientation of attention (microstate D).
科研通智能强力驱动
Strongly Powered by AbleSci AI