Network meta-analysis : comparative efficacy of diverse aspirin dosages and heparin in mitigating placenta-mediated pregnancy complications

Anticoagulant therapies, particularly combinations of ASA and LMWH, effectively mitigate PMPC. The < 100 mg/day ASA + LMWH regimen demonstrates optimal efficacy in reducing severe PE and fetal loss, while ≥ 100 mg/day ASA + LMWH is strongly supported by TSA. These findings inform clinical decisions for PMPC prophylaxis.