Enzymatic Drug Therapy for Salmonella Biofilm Disruption

With the growing human population, the risk of bacterial infections has become a common threat. Salmonellosis, caused by Gram-negative Salmonella bacteria, is responsible for a significant number of bacterial deaths, largely due to the formation of mature biofilms. This strain of bacteria can be treated with both enzymatic and non-enzymatic therapies. Enzymatic therapeutics involve the use of enzymes, whereas non-enzymatic therapeutics do not. Non-enzymatic therapies have their own advantages and limitations. However, enzymatic therapeutics, such as single and combinatorial drugs, are reliable compounds that can be used to disrupt the formation and growth of Salmonella biofilms and reduce their pathogenic activity.