Assessment of the efficacy and safety of platelet rich plasma gel injection in facial rejuvenation and wrinkles

Background: Changes in the three-dimensional geometry of the underlying structures contribute to the ageing process of the human face, just as the skin's surface textural wrinkling does.Objective: To evaluate the efficacy and safety of platelet rich plasma gel injection in facial rejuvenation and facial wrinkles.Methods: This study was carried out on 10 subjects presented by facial wrinkles.Patients were subjected to platelet rich plasma gel injection after taking an informed consent.They were assessed clinically by global assessment scale before treatment and at the end of follow up period.Results: After administration of plasma gel, all subjects significantly improved clinically immediately.This finding confirmed by significant improvement of global assessment scale.Conclusions: Plasma gel seem to be safe, effective and well tolerated in treatment of facial wrinkles and rejuvenation.