生物
寄主(生物学)
病毒感染
计算生物学
病毒进入
病毒
细胞生物学
病毒学
病毒复制
遗传学
作者
Fabian Wendt,Emanuela S. Milani,Bernd Wollscheid
出处
期刊:Advances in Virus Research
日期:2021-01-01
卷期号:: 105-134
被引量:5
标识
DOI:10.1016/bs.aivir.2021.03.002
摘要
The cellular surfaceome and its residing extracellularly exposed proteins are involved in a multitude of molecular signaling processes across the viral infection cycle. Successful viral propagation, including viral entry, immune evasion, virion release and viral spread rely on dynamic molecular interactions with the surfaceome. Decoding of these viral-host surfaceome interactions using advanced technologies enabled the discovery of fundamental new functional insights into cellular and viral biology. In this review, we highlight recently developed experimental strategies, with a focus on spatial proteotyping technologies, aiding in the rational design of theranostic strategies to combat viral infections.
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