甲巯咪唑
校准曲线
色谱法
线性相关
化学
校准
甲状腺
检出限
数学
生物
内分泌学
统计
作者
Grażyna Chwatko,Veerle Darras,Edward Bald
标识
DOI:10.1080/19440049.2014.905878
摘要
A simple, rapid, reproducible and sensitive method based on HPLC with ultraviolet detection was developed for the determination of methimazole (MMI) in animal tissues and plasma samples. Under the optimum experimental conditions, the calibration curves for MMI were linear in the tested range 0.5–20 mg kg−1 tissue sample (mg l−1 plasma) with correlation coefficients better than 0.99. The performance of the proposed method was tested for the determination of MMI levels in brain, liver, thyroid gland and plasma of MMI-treated hens, as well as in their eggs and embryos. The proposed method reduces time and simplifies the sample preparation procedure.
科研通智能强力驱动
Strongly Powered by AbleSci AI