Highly Efficient, Regio- and Stereoselective Alcoholysis of Epoxides Catalyzed with Iron(III) Chloride

An efficient, catalytic, simple and mild method for the conversion of epoxides into their corresponding ß-alkoxy alcohols was performed in primary, secondary and tertiary alcohols and in the presence of catalytic amounts of ferric chloride. The ß-alkoxy alcohols were obtained with high stereo- and regioselectivity and in good to excellent yields.