The ever growing complexity of trophoblast epigenetics

Mammalian placentation is closely regulated by the actions of trophoblast cells at the time of implantation. Invasion of trophoblast into uterine tissue is an essential process in placentation and appropriate fetal development. Since human trophoblast is responsible for appropriate fetal growth, it is of major interest in the field of medicine, particularly in understanding how it is influenced by different processes and environmental conditions. This review is sought to give an insight into the complexity of trophoblast epigenetics and different processes and environmental factors controlling it.