医学
心脏病学
内科学
心源性休克
右冠状动脉
经皮冠状动脉介入治疗
心肌梗塞
罪魁祸首
传统PCI
ST高程
动脉
冠状动脉造影
作者
Giuseppe Femia,A. Faour,J. Assad,L. Sharma,Hanan Idris,O. Gibbs,P. Pender,Dominic Y. Leung,A. Hopkins,R. Rajaratnam,C. Juergens,C. Mussap,John K. French,Sidney Lo
摘要
Abstract Objective To evaluate the prognostic significance of culprit lesion location in dominant right coronary artery (RCA) ST‐elevation myocardial infarction (STEMI). Background In RCA STEMI, proximal culprit lesions have been shown to have higher rates of acute complications such as bradycardia and cardiogenic shock (CS) but data on mortality is limited. Methods We retrospectively identified and analyzed data from consecutive patients with a dominant RCA STEMI who underwent either primary or rescue percutaneous coronary intervention (PCI) between January 2003 and December 2016. We compared the rates of sustained ventricular tachycardia (VT), CS, intra‐aortic balloon pump (IABP), temporary cardiac pacing (TCP) and death between culprit lesions located proximal and distal to the origin of the last right ventricular (RV) marginal artery >1 mm in diameter. Results The 939 patients were included; 599 (63.7%) had a proximal lesion and 340 (36.3%) had a nonproximal lesion. The 801 (85.3%) underwent primary PCI and 138 (14.7%) underwent rescue PCI. There was no difference in first medical contact to balloon or fibrinolysis times between the groups; p = .98 and .71. There was no significant difference in the rate of sustained VT (3.0%vs. 3.2%, p = .85) but proximal lesions were more likely to develop CS (10.9%vs. 5.8%, p = .01), require IABP (7.3%vs.2.9%, p < .01) and TCP (6.3%vs. 2.6%, p = .01). Thirty‐day mortality was higher for proximal lesions (5.0%vs. 0.9%, p < .01) particularly for those with CS (35.3%vs. 10.0%, p = .05). Conclusion Culprit lesions located proximal to the origin of the last RV marginal artery had a higher rate of acute complications such as CS and mortality.
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