From Loops to Caps: Discriminating Peptide Binding to Distinct G-Quadruplex Tetrads Using 5-Furyl-2′-Deoxyuridine Fluorescent Probes

We report the use of 5-furyl-2′-deoxyuridine (5FU) as a fluorescent probe to distinguish ligand binding to distinct G-quadruplex tetrads. Site-specific incorporation of 5FU into T95-2T at the capping regions enabled...