医学
弹性成像
接收机工作特性
弹性(物理)
病变
放射科
乳房成像
标准差
超声波
核医学
乳腺癌
病理
内科学
乳腺摄影术
癌症
统计
复合材料
材料科学
数学
作者
A. Athanasiou,A. Tardivon,Mickaël Tanter,Brigitte Sigal‐Zafrani,Jérémy Bercoff,Daniel Thomas,Jean‐Luc Gennisson,Mathias Fink,S. Neuenschwander
出处
期刊:Radiology
[Radiological Society of North America]
日期:2010-07-01
卷期号:256 (1): 297-303
被引量:457
标识
DOI:10.1148/radiol.10090385
摘要
To determine the appearance of breast lesions at quantitative ultrasonographic (US) elastography by using supersonic shear imaging (SSI) and to assess the correlation between quantitative values of lesion stiffness and pathologic results, which were used as the reference standard.This study was approved by the French National Committee for the Protection of Patients Participating in Biomedical Research Programs. All patients provided written informed consent. Conventional US and SSI quantitative elastography were performed in 46 women (mean age, 57.6 years; age range, 38-71 years) with 48 breast lesions (28 benign, 20 malignant; mean size, 14.7 mm); pathologic results were available in all cases. Quantitative lesion elasticity was measured in terms of the Young modulus (in kilopascals). Sensitivity, specificity, and area under the curve were obtained by using a receiver operating characteristic curve analysis to assess diagnostic performance.All breast lesions were detected at SSI. Malignant lesions exhibited a mean elasticity value of 146.6 kPa +/- 40.05 (standard deviation), whereas benign ones had an elasticity value of 45.3 kPa +/- 41.1 (P < .001). Complicated cysts were differentiated from solid lesions because they had elasticity values of 0 kPa (no signal was retrieved from liquid areas).SSI provides quantitative elasticity measurements, thus adding complementary information that potentially could help in breast lesion characterization with B-mode US.
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