The Cell of Dermal Papilla at a Glance

Hair follicle( HF) is an affiliated organ of the skin which possess the ability of self-renewal and periodic growth. Complete structure of HF is significant regarding to warm-keeping and the appearance beauty. There are a group of mesenchymal cells existing in the hair bulb,called dermal papilla cells( DPC). DPC plays an important role in inducing the formation of HFs in both HF morphogenesis and postnatal hair cycle. Deletion of DPC leads to the failure of HF formation. In postnatal hair cycle,DPC interacts with follicular epithelial cells and directly or indirectly induce the periodic growth of hair follicles. Through studying the characteristics and biological function of DPC,the development and regeneration of HFs could be further understood.