Biodegradation characterization of a pyridine-degrading strain

Pyridine is a intractable toxic organic and a N-heterocycle compound.The biodegradation characterization of pyridine was investigated in a pure culture using a pyridine-degrading strain isolated from the soil in a pesticide plant.The strain was identified as Paracoccus sp.on the basis of a partial 16SrRNA gene sequence analysis and designated as strain KT-5.Analysis of pyridine degradation indicated that KT-5 was able to utilize pyridine as the sole source of carbon,energy and nitrogen.High concentrations of pyridine(1.331 g/L) did not inhibit the growth of KT-5.KT-5 showed different degradation characteristics with different initial pyridine concentrations.When the pyridine concentration was below 900 mg/L,the initial KT-5 degradation rate was higher than the final degradation rate.When the pyridine concentration was above 0.9 g/L,the initial KT-5 degradation rate was lower than the final degradation rate.