化学
贝克曼重排
酰胺
加合物
四唑
级联
光延反应
组合化学
酰亚胺
立体化学
催化作用
有机化学
色谱法
作者
Yongjiao Wei,Yinghui Liu,Lan‐Gui Xie
标识
DOI:10.1016/j.cclet.2021.10.020
摘要
The Beckmann rearrangement has been predominantly studied for the synthesis of amide and lactam. By strategically using the in situ generated Appel's salt or Mitsunobu's zwitterionic adduct as the dehydrating agent, a series of Beckmann rearrangement and following cascade reactions have been developed herein. The protocol allows the conversion of various ketoximes into amide, thioamide, tetrazole and imide products in modular procedures. The generality and tolerance of functionalities of this method have been demonstrated.
科研通智能强力驱动
Strongly Powered by AbleSci AI