卟啉
合成子
化学
超分子化学
组合化学
高分子
产量(工程)
有机合成
催化作用
有机化学
分子
生物化学
冶金
材料科学
作者
Valentinos Mouarrawis,Simon Mathew,Eva J. Meeus,Bas de Bruin,Joost N. H. Reek
标识
DOI:10.1142/s1088424621500504
摘要
A facile synthetic strategy was developed for the synthesis of meso -tetrakis(4-formyl-phenyl)porphyrin and meso -tetrakis(3-formylphenyl)porphyrin from commercially available starting materials. This method gives facile access to practical amounts of these synthons in high purity and good overall yield, without employing laborious chromatographic separations. The reduction of the respective carboxylic acid-functionalized porphyrins by LiAlH 4 afforded the tetra(benzylalcohol)porphyrin intermediates, subsequently utilized in a Parikh-Doering oxidation to selectively afford the desired tetraformylated products. The inherent ease of synthesis of these porphyrin building blocks provides a convenient pathway for the synthesis of various macromolecular and supramolecular architectures for applied chemical technologies.
科研通智能强力驱动
Strongly Powered by AbleSci AI