医学
改良兰金量表
内科学
组织纤溶酶原激活剂
神经学
中性粒细胞与淋巴细胞比率
溶栓
淋巴细胞
缺血性中风
缺血
心肌梗塞
精神科
作者
Yiyun Weng,Jingyu Hu,Jinhan Ren,Honghao Huang,Chenguang Yang,Jiamin Shen,Wenjing Pan,Fangyue Sun,Haojie Qiu,Yufan Gao,Shengqi Li,Xuerong Huang,Guangyong Chen
标识
DOI:10.1007/s12640-021-00382-6
摘要
The main purpose of this study was to investigate the dynamic changes of neutrophils-lymphocytes ratios (NLRs) in patients with acute ischemic stroke (AIS) and their relationships with 3-month prognostic outcomes. Two hundred ninety-one patients with AIS were included in this study, followed up for 3 months. At admission, 1 and 7 days after recombinant tissue plasminogen activator (r-tPA) injection, blood samples were obtained. Outcome events included excellent outcome, good outcome, and death defined as modified Rankin Scale (mRS) scores of 0–1, 0–2, and 6 respectively. NLRs measured in admission and 7 days after r-tPA treatment were associated with prognosis outcome after 3 months. Twenty-four-hour NLR is an excellent indicator in forecasting (excellent outcome’s the areas under the curve (AUC) = 0.725; good outcome AUC = 0.742; death AUC = 0.759). In addition, we were surprised to find that dynamic increase in NLR within 24 h is significantly related to excellent and good outcomes. Twenty-four-hour NLR is related to the severity of AIS and poor prognosis, which can help early risk stratification. We can predict the prognosis of AIS more accurately. Compared with previous studies, our study has shown the dynamic changes of NLR and its relationship with NIHSS and multiple prognostic.
科研通智能强力驱动
Strongly Powered by AbleSci AI