Influence of Calcium and Strontium Carriers for Radioactive Strontium Deposition in Bone

The influence of stable carriers on the deposition of radioactive strontium in the bone was investigated. The deposition of calcium-45 or strontium-89 was observed to depend on the solubilities of their salts at the time of administration. Therefore, the concentrations of radioactive strontium in bone calcium were calculated on the basis of calcium content in soluble fraction of foods. The interference of calcium carrier on the deposition of strontium-89 in rats femurs could be recognized only under the calcium deficient condition. Using tissue culture of chick embryonic bone, the uptake of strontium-89 was evidently depressed by the addition of strontium carrier in the medium rather than by calcium carrier.